From artificial surfaces to living cells, Molecular Nano Dynamics, Vol. I and Vol. II explores more than 40 important methods for dynamic observation of the nanoscale. Edited by absolute science greats from Japan, this two–volume set covers all important aspects of this topic: nanoscale spectroscopy and characterization tools, nanostructure dynamics, single living cell dynamics, active surfaces, and single crystals. Destined to be the definitive reference work on nanoscale molecular dynamics and their observation for years to come, this is a must–have reference for chemists, physicists, physical chemists, theoretical chemists, and materials scientists. About the Author Hiroshi Fukumura studied the biocompatibility of polymers in the Government Industrial Research Institute of Osaka from 1983 to 1988. He became an Assistant Professor at the Kyoto Institute of Technology in 1988, then moved to the Department of Applied Physics of Osaka University in 1991, where he worked on the mechanism of laser ablation and laser molecular implantation. Since 1998, he is Professor in the Department of Chemistry at Tohoku University. His current interests include molecular physical chemistry employing ultra–fast spectroscopy and scanning tunneling microscopy.
Masahiro Irie received his B.S. and M.S. degrees from Kyoto University and his Ph.D. degree in radiation chemistry from Osaka University. He started his research on photochemistry at Hokkaido University in 1970 and went on to Osaka University. In 1988 he was appointed to Professor at Kyushu University, where he initiated the study of photochromic diarylethene derivatives. He is currently interested in developing single–crystalline photochromism and single–molecule photochemistry using diarylethene derivatives.
Yasuhiro Iwasawa pioneered the integration of modern surface science and organometallic chemistry into surface chemistry and catalysis on the atomic/molecular scale, and he has a leading position in the creation of the new research field of catalysis and surface chemistry at oxide surfaces by XAFS and SPM techniques. His honors include the Japan IBM Science Award (1990), Inoue Prize for Science (1996), Catalysis Society of Japan Award (1999), The Surface Science Society of Japan Award (2000), Medal with Purple Ribbon (2003), and the Chemical Society of Japan Award (2004).
Hiroshi Masuhara held a Professorship at the Kyoto Institute of Technology (1984–1991) before returning to Osaka University as Professor in the Department of Applied Physics. With his research, he opened a whole new field on laser nanospectroscopy, nanophotochemistry and laser nanoablation. In addition to his position in Osaka, he joined the Hamano Life Science Research Foundation in Kobe for research activities in bioscience and biotechnology. He has edited ten English and three Japanese books on topics ranging from photochemistry and spectroscopy to micro– and nanophotonics.
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TaGs: Medicine and Health, Molecular, Volume
This fascinating book draws it subject matter from a range of relevant disciplines that extend from molecular nutrition, nutritional sciences, and nutrition dietetics through to genetics, genomics, and anthropology. It presents a vital portrait of the absolutely fundamental role that nutrition has played and continues to play in shaping who and what human beings are, as well as where they evolved from, and where they may be heading as a species. Molecular Nutrition: Nutrition and the Evolution of Humankind:
• Blends coverage of the molecular mechanisms that underpin nutrient-gene interactions with evolutionary theory
• Takes a molecular biological approach to problem solving, and moves nutrition away from its dietetic and anthropological origins to the front lines of genomic research
• Covers key concepts in molecular biology; the –omics revolution and bioinformatics; recent human evolution; molecular mechanisms of gene-nutrient interactions; the importance of nutrients and genomics in disease; the evolution of micronutrient metabolism, protein structure, and human disease; nutrients and the human lifecycle; contemporary dietary patterns; leading-edge laboratory tools in nutrigenomics and human evolutionary studies
Written by an internationally recognised expert in the field, Molecular Nutrition: Nutrition and the Evolution of Humankind is an invaluable text and reference book for a wide range of teachers, students, and researchers.
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TaGs: Medicine and Health, Molecular
This proceedings volume details both current and future research and development initiatives in nano-biomedical engineering, arguably the most important technology of the world in the 21st century. It deals with the following four groups of nano-biomedical engineering such as: nano-biomechanics, nano-bioimaging, nano-biodevices, and nano-biointervention. Consisting of a compilation of studies conducted by group members of the Tohoku University Global Center of Excellence Program, with specially coordinated funding from the Japanese Government, the papers emphasize the integration of research and education collaboration between engineering and medicine, and showcase Japan’s top-level research in the field of nano-biomedical engineering.
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TaGs: Engineering, Medicine and Health, Nanomedicine
Nanodiamonds: Applications in Biology and Nanoscale Medicine highlights the translation of nanodiamonds toward clinical relevance and medical applications. Integrating a spectrum of internationally-recognized experts currently developing these technologies, this book fits as a cornerstone of this exciting field. These include contributions from clinician scientists working at the interface of medicine and nanotechnologies which discuss the critical and requisite properties of nanomaterials, in a concise and cohesive manner. Nanodiamonds: Applications in Biology and Nanoscale Medicine provides a multidisciplinary overview of nanodiamonds and there uses for scientific, engineering and clinical audiences alike.
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TaGs: Applications, Medicine and Health, Nanoscale
This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. It will advance knowledge of nanoscale science and engineering by efficiently employing quantitative tools for fundamental biomedical engineering and biological science research. The book starts by introducing the concept of nanomedicine, and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth, and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling, and AFM engineering. This book demonstrates how systems engineering, which has been very successful in conventional engineering, may help with nanomedicine.
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TaGs: Approach, Engineering, Medicine and Health, Nanomedicine, Systems
An important and exciting aspect in the newly developing field of nanomedicine is the use of nanoparticle drug delivery systems allowing for innovative therapeutic approaches. Due to their small size, these drug delivery systems are promising tools in therapeutic approaches such as selective or targeted drug delivery towards a specific tissue or organ, enhanced drug transport across biological barriers, and intracellular drug delivery. This timely book provides an overview of possible therapeutic applications. The first part of the book highlights general properties of and phenomena observed with nanoparticles, and the subsequent consequences for applications in drug delivery. The second part focuses on the therapeutic approaches that are possible through the use of nanoparticles, with each chapter discussing a specific disease (e.g. diabetes, cancer, inflammation, etc.) and the relevant therapeutic approaches based on the design of nanoparticulate drug delivery systems. Written in a concise manner, readers will gain an insight into the basics of nanoparticle preparation as well as a more detailed account of what is therapeutically feasible by using nanoparticle approaches.
Contents: General Aspects of Nanotherapeutics: Nanocarriers in Drug Delivery – Design, Manufacture and Physicochemical Properties (C Schmidt & A Lamprecht); Transport Across Biological Barriers (N Nafee et al.); Targeting Approaches (S Cammas-Marion); Disease-Related Approaches by Nanotherapeutics: Nanoscale Cancer Therapeutics (Y Pellequer & A Lamprecht); Nanotherapeutics for Skin Diseases (N Atrux-Tallau et al.); Nanoparticles for Oral Vaccination (J M Irache et al.); Nanoparticles: Therapeutic Approaches for Bacterial Diseases (B Moulari); Nanoparticle Therapy in Parasites Diseases: Possibility and Reality! (M Larabi); Nanocarriers in the Therapy of Inflammatory Disease (A Lamprecht).
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TaGs: Concepts, Delivery, Drug, Medicine and Health, Nanoscience, Nanotherapeutics
Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. This book highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology.
* Describes the newest, molecular aspects of neurological disorders
* Provides an introduction to neurological disorders for basic scientists
* Updates clinicians and clinical researchers on the most recent developments
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TaGs: Medicine and Health, Molecular, Neurology
The origin of life represents one of the most challenging problems of science. However, in recent years modern biology, chemistry and physics have found a combined framework within which fundamental aspects of this problem can be formulated at the molecular level. Even though a detailed reconstruction of the historical course of the origin of life remains impossible the general principles and laws governing the transition from the non-living to the living can now be elucidated and subjected to experimental test. The molecular view of evolution presented in this book provides in essence a physical counterpart to the classical Darwinian theory of evolution, and shows how this new approach can be applied to the problem of molecular self-organization and evolution. The book is intended both as an expository monograph and as an introductory text for advanced students of physics, chemistry and biology. As such, it represents the first cohesive presentation of the new theory of the origin of life.
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TaGs: Evolution, Life, Medicine and Health, Molecular, Theory
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